Article
Transcriptional mechanisms in anterior pituitary cell differentiation.
Current opinion in genetics & development - 1 Oct 1994
Rhodes S J, DiMattia G E, Rosenfeld M G
Abstract excerpt
Development of the anterior pituitary gland involves the establishment of five distinct cell lineages which are each characterized by the expression of specific trophic hormone genes. Recent studies of the thyrotrope, somatotrope, and lactotrope cell types have investigated the molecular decisions responsible for the commitment and differentiation of these cell types and have characterized the regulatory...
Topics
- Animals
- Base Sequence
- Cell Differentiation
- DNA
- DNA-Binding Proteins
- Gene Expression Regulation, Developmental
- Humans
- Molecular Sequence Data
- Phenotype
- Pituitary Gland, Anterior
- Pituitary Hormones, Anterior
