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Article

Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response.

AIDS (London, England) - 24 Jan 2003

Brumme Zabrina L, Dong Winnie W Y, Chan Keith J, Hogg Robert S, Montaner Julio S G, O'Shaughnessy Michael V, Harrigan P Richard

Abstract excerpt

OBJECTIVE: Single nucleotide polymorphisms (SNP) in the genes encoding the human CX3CR1 chemokine receptor and the P-glycoprotein multidrug transporter have been associated with accelerated disease progression in untreated individuals and implicated in therapeutic response, respectively. This retrospective study assessed the influence of SNP in the CX3CR1 and MDR-1 genes on initial virological and immunological...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12545080
DOI: 10.1097/00002030-200301240-00010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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