Article
Exploring the roles of DNA methylation in the metal-reducing bacterium Shewanella oneidensis MR-1.
Journal of bacteriology - 1 Nov 2013
Bendall Matthew L, Luong Khai, Wetmore Kelly M, Blow Matthew, Korlach Jonas, Deutschbauer Adam, Malmstrom Rex R
Abstract excerpt
We performed whole-genome analyses of DNA methylation in Shewanella oneidensis MR-1 to examine its possible role in regulating gene expression and other cellular processes. Single-molecule real-time (SMRT) sequencing revealed extensive methylation of adenine (N6mA) throughout the genome. These methylated bases were located in five sequence motifs, including three novel targets for type I restriction/modification...
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