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Article

DNA Methylation Assessed by SMRT Sequencing Is Linked to Mutations in Neisseria meningitidis Isolates.

PloS one - 1 Jan 2015

Sater Mohamad R Abdul, Lamelas Araceli, Wang Guilin, Clark Tyson A, Röltgen Katharina, Mane Shrikant, Korlach Jonas, Pluschke Gerd, Schmid Christoph D

Abstract excerpt

The Gram-negative bacterium Neisseria meningitidis features extensive genetic variability. To present, proposed virulence genotypes are also detected in isolates from asymptomatic carriers, indicating more complex mechanisms underlying variable colonization modes of N. meningitidis. We applied the Single Molecule, Real-Time (SMRT) sequencing method from Pacific Biosciences to assess the genome-wide DNA...

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Identifiers

PMID: 26656597
DOI: 10.1371/journal.pone.0144612
PMCID: PMC4676702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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