Article
FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.
Carcinogenesis - 1 Aug 2010
Barnholtz-Sloan Jill S, Shetty Priya B, Guan Xiaowei, Nyante Sarah J, Luo Jingchun, Brennan Donal J, Millikan Robert C
Abstract excerpt
Twenty-nine single-nucleotide polymorphisms (SNPs) from previously published genome-wide association studies (GWAS) and multiple ancestry informative markers were genotyped in the Carolina Breast Cancer Study (CBCS) (742 African-American (AA) cases, 1230 White cases; 658 AA controls, 1118 White controls). In the entire study population, 9/10 SNPs in fibroblast growth factor receptor 2 (FGFR2) were significantly...
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