Association of STAT4 polymorphisms with susceptibility to type-1 autoimmune hepatitis in the Japanese population.

doi:10.1371/journal.pone.0071382

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Article

Association of STAT4 polymorphisms with susceptibility to type-1 autoimmune hepatitis in the Japanese population.

PloS one - 1 Jan 2013

Migita Kiyoshi, Nakamura Minoru, Abiru Seigo, Jiuchi Yuka, Nagaoka Shinya, Komori Atsumasa, Hashimoto Satoru, Bekki Shigemune, Yamasaki Kazumi, Komatsu Tatsuji, Shimada Masaaki, Kouno Hiroshi, Hijioka Taizo, Kohjima Motoyuki, Nakamuta Makoto, Kato Michio, Yoshizawa Kaname, Ohta Hajime, Nakamura Yoko, Takezaki Eiichi, Nishimura Hideo, Sato Takeaki, Ario Keisuke, Hirashima Noboru, Oohara Yukio, Naganuma Atsushi, Muro Toyokichi, Sakai Hironori, Mita Eiji, Sugi Kazuhiro, Yamashita Haruhiro, Makita Fujio, Yatsuhashi Hiroshi, Ishibashi Hiromi, Yasunami Michio

Abstract excerpt

BACKGROUND/AIMS: Recent studies demonstrated an association of STAT4 polymorphisms with autoimmune diseases including systemic lupus erythematosus and rheumatoid arthritis, indicating multiple autoimmune diseases share common susceptibility genes. We therefore investigated the influence of STAT4 polymorphisms on the susceptibility and phenotype of type-1 autoimmune hepatitis in a Japanese National Hospital...

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PMID: 23990947
DOI: 10.1371/journal.pone.0071382
PMCID: PMC3750035

Genes

STAT4

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