Article
Glutamine synthetase in astrocytes from entorhinal cortex of the triple transgenic animal model of Alzheimer's disease is not affected by pathological progression.
Biogerontology - 1 Dec 2013
Yeh Chia-Yu, Verkhratsky Alexei, Terzieva Slavica, Rodríguez José J
Abstract excerpt
Astrocytes are fundamental for brain physiology and pathology, including Alzheimer's disease (AD). Among their functions, the maintenance of glutamate balance via the glutamate-glutamine (Glu-Gln) shuttle is critical for both normal cognitive functions and excitotoxicity relevant for AD progressi...
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