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Article

Therapeutic effect of exogenous hsp70 in mouse models of Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2014

Bobkova Natalia V, Garbuz David G, Nesterova Inna, Medvinskaya Natalia, Samokhin Alexander, Alexandrova Irina, Yashin Valerii, Karpov Vadim, Kukharsky Michail S, Ninkina Natalia N, Smirnov Andrey A, Nudler Evgeny, Evgen'ev Michael

Abstract excerpt

Brain deterioration resulting from "protein folding" diseases, such as the Alzheimer's disease (AD), is one of the leading causes of morbidity and mortality in the aging human population. Heat shock proteins (Hsps) constitute the major cellular quality control system for proteins that mitigates the pathological burden of neurotoxic protein fibrils and aggregates. However, the therapeutic effect of Hsps has not...

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PMID: 23985416
DOI: 10.3233/JAD-130779

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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