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Article

Germline variation in NCF4, an innate immunity gene, is associated with an increased risk of colorectal cancer.

International journal of cancer - 15 Mar 2014

Ryan Bríd M, Zanetti Krista A, Robles Ana I, Schetter Aaron J, Goodman Julie, Hayes Richard B, Huang Wen-Yi, Gunter Mark J, Yeager Meredith, Burdette Laurie, Berndt Sonja I, Harris Curtis C

Abstract excerpt

Chronic inflammation has been implicated in the etiology of colorectal adenoma and cancer; however, few key inflammatory genes mediating this relationship have been identified. In this study, we investigated the association of germline variation in innate immunity genes in relation to the risk of colorectal neoplasia. Our study was based on the analysis of samples collected from the prostate, lung, colorectal and...

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Source

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Identifiers

PMID: 23982929
DOI: 10.1002/ijc.28457
PMCID: PMC3947351

Genes

NCF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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