Article
Association between autozygosity and major depression: stratification due to religious assortment.
Behavior genetics - 1 Nov 2013
Abdellaoui Abdel, Hottenga Jouke-Jan, Xiao Xiangjun, Scheet Paul, Ehli Erik A, Davies Gareth E, Hudziak James J, Smit Dirk J A, Bartels Meike, Willemsen Gonneke, Brooks Andrew, Sullivan Patrick F, Smit Johannes H, de Geus Eco J, Penninx Brenda W J H, Boomsma Dorret I
Abstract excerpt
The effects of inbreeding on the health of offspring can be studied by measuring genome-wide autozygosity as the proportion of the genome in runs of homozygosity (F roh) and relate F roh to outcomes such as psychiatric phenotypes. To successfully conduct these studies, the main patterns of variation for genome-wide autozygosity between and within populations should be well understood and accounted for. Within...
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