Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Maternal inheritance in recurrent early-onset depression.

Psychiatric genetics - 1 Feb 2010

Bergemann Eric R, Boles Richard G

Abstract excerpt

Major depressive disorder (MDD) is believed to have a genetic factor in its pathogenesis. On the basis of studies in MDD showing brain energy depletion and maternal inheritance in some families, we hypothesize that some of the genetic factor is likely maternally inherited on the mitochondrial DNA (mtDNA). Six hundred and seventy-two pedigrees from the Genetics of Recurrent Early-Onset Depression project were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Confidence Intervals
Share to Depressive Disorder, Major
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Family

Share to Mood Disorders

Share to Mothers

Share to Odds Ratio

Share to Recurrence

Source

Identifiers

PMID: 20010317
DOI: 10.1097/YPG.0b013e3283351153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Maternal inheritance in recurrent early-onset depression.PMID 20010317Read ↗

Malignancy of recurrent, early‐onset major depression: A family studySemantic proximity Read ↗

A high predisposition to depression and anxiety in mothers and other matrilineal relatives of children with presumed maternally inherited mitochondrial disorders.Semantic proximity Read ↗

Mitochondrial inheritance in depression, dysmotility and migraine?Semantic proximity Read ↗

Genetic segregation analysis of recurrent, early-onset major depression: evidence for single major locus transmission.Semantic proximity Read ↗

Molecular Signatures of Major DepressionSemantic proximity Read ↗

Depression spectrum disease, I: The role of gene-environment interaction.Semantic proximity Read ↗

Single-Nucleotide Polymorphisms in Genes Maintaining the Stability of Mitochondrial DNA Affect the Occurrence, Onset, Severity and Treatment of Major Depressive Disorder.Semantic proximity Read ↗

Familial Risk Factors in Relation to Recurrent Depression Among Former Adolescent Psychiatric Inpatients.Semantic proximity Read ↗

Relationship between circulating mitochondrial DNA and microRNA in patients with major depressionSemantic proximity Read ↗

Clinical characteristics of major depressive disorder run in families--a community study of 933 mothers and their children.Semantic proximity Read ↗

Major depression in adolescent children consecutively diagnosed with mitochondrial disorder.Semantic proximity Read ↗

Mitochondria DNA change and oxidative damage in clinically stable patients with major depressive disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.