Associations between single nucleotide polymorphisms in thyroid hormone transporter genes (MCT8, MCT10 and OATP1C1) and circulating thyroid hormones.

doi:10.1016/j.cca.2013.08.017

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Associations between single nucleotide polymorphisms in thyroid hormone transporter genes (MCT8, MCT10 and OATP1C1) and circulating thyroid hormones.

Clinica chimica acta; international journal of clinical chemistry - 21 Oct 2013

Roef Greet L, Rietzschel Ernst R, De Meyer Tim, Bekaert Sofie, De Buyzere Marc L, Van daele Caroline, Toye Kaatje, Kaufman Jean-Marc, Taes Youri E

Abstract excerpt

BACKGROUND: Thyroid hormone (TH) action takes place intracellularly; therefore, transport across the plasma membrane by specific TH transporters, such as MCT8, MCT10 and OATP1C1, is necessary. Several single nucleotide polymorphisms (SNPs) in these genes were reported to be associated with TH concentrations; however, results have been inconsistent. METHODS: Six SNPs in TH transporter genes (rs5937843-G/T and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Transport Systems, Neutral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Monocarboxylic Acid Transporters

Share to Organic Anion Transporters

Share to Symporters

Share to Thyroid Gland

Share to Thyrotropin

Share to Thyroxine

Share to Triiodothyronine

Source

Open in PubMed

Identifiers

PMID: 23978482
DOI: 10.1016/j.cca.2013.08.017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations between single nucleotide polymorphisms in thyroid hormone transporter genes (MCT8, MCT10 and OATP1C1) and circulating thyroid hormones.PMID 23978482Read ↗

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulationSemantic proximity Read ↗

A locus on chromosome 1p36 is associated with thyrotropin and thyroid function as identified by genome-wide association study.Semantic proximity Read ↗

The Effects of Common Genetic Variation in 96 Genes Involved in Thyroid Hormone Regulation on TSH and FT4 Concentrations.Semantic proximity Read ↗

Disorder of thyroid hormone transport into the tissues.Semantic proximity Read ↗

Molecular aspects of thyroid hormone transporters, including MCT8, MCT10, and OATPs, and the effects of genetic variation in these transporters.Semantic proximity Read ↗

Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function.Semantic proximity Read ↗

Thyroid hormone transporters in health and disease.Semantic proximity Read ↗

A large-scale association analysis of 68 thyroid hormone pathway genes with serum TSH and FT4 levels.Semantic proximity Read ↗

Identification and consequences of polymorphisms in the thyroid hormone receptor alpha and beta genes.Semantic proximity Read ↗

Gene polymorphisms and thyroid hormone signaling: implication for the treatment of hypothyroidism.Semantic proximity Read ↗

Single Nucleotide Polymorphisms in Thyroid Hormone Transporter Genes MCT8, MCT10 and Deiodinase DIO2 Contribute to Inter-Individual Variance of Executive Functions and Personality Traits.Semantic proximity Read ↗

Thyroid hormone transport and metabolism by organic anion transporter 1C1 and consequences of genetic variation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.