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Article

Thyroid hormone transport and metabolism by organic anion transporter 1C1 and consequences of genetic variation.

Endocrinology - 1 Oct 2008

van der Deure Wendy M, Hansen Pia Skov, Peeters Robin P, Kyvik Kirsten Ohm, Friesema Edith C H, Hegedüs Laszlo, Visser Theo J

Abstract excerpt

Organic anion transporting polypeptide (OATP) 1C1 has been characterized as a specific thyroid hormone transporter. Based on its expression in capillaries in different brain regions, OATP1C1 is thought to play a key role in transporting thyroid hormone across the blood-brain barrier. For this reason, we studied the specificity of iodothyronine transport by OATP1C1 in detail by analysis of thyroid hormone uptake...

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Identifiers

PMID: 18566113
DOI: 10.1210/en.2008-0430

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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