Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Low ABCB1 gene expression is an early event in colorectal carcinogenesis.

PloS one - 1 Jan 2013

Andersen Vibeke, Vogel Ulla, Godiksen Sine, Frenzel Franz B, Sæbø Mona, Hamfjord Julian, Kure Elin, Vogel Lotte K

Abstract excerpt

The ABCB1/MDR1 gene product ABCB1/P-glycoprotein is implicated in the development of colorectal cancer (CRC). NFKB1 encodes transcription factors regulating expression of a number of genes including ABCB1. We have previously found association between the ABCB1 C-rs3789243-T polymorphism and CRC r...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoma
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Share to Carcinogenesis

Share to Carcinoma

Share to INDEL Mutation

Share to NF-kappa B p50 Subunit

Source

Open in PubMed Open full text

Identifiers

PMID: 23977225
DOI: 10.1371/journal.pone.0072119
PMCID: PMC3747088

Genes

ABCB1
NFKB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23977225-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Low ABCB1 gene expression is an early event in colorectal carcinogenesis.PMID 23977225Read ↗

High ABCC2 and low ABCG2 gene expression are early events in the colorectal adenoma-carcinoma sequence.Semantic proximity Read ↗

The multidrug resistance 1 (MDR1) gene polymorphism G-rs3789243-A is not associated with disease susceptibility in Norwegian patients with colorectal adenoma and colorectal cancer; a case control study.Semantic proximity Read ↗

Novel understanding of ABC transporters ABCB1/MDR/P-glycoprotein, ABCC2/MRP2, and ABCG2/BCRP in colorectal pathophysiology.Semantic proximity Read ↗

ABCB1/MDR1 gene polymorphism and colorectal cancer risk: a meta-analysis of case-control studies.Semantic proximity Read ↗

ABCG2 Gene and ABCG2 Protein Expression in Colorectal Cancer—In Silico and Wet AnalysisSemantic proximity Read ↗

Polymorphisms in NFkB, PXR, LXR and risk of colorectal cancer in a prospective study of Danes.Semantic proximity Read ↗

ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/β-Catenin, Notch and PI3K/Akt Signaling PathwaysSemantic proximity Read ↗

Associations between the functional polymorphisms in the ABCB1 transporter gene and colorectal cancer risk: a case-control study in Turkish population.Semantic proximity Read ↗

A comprehensive investigation on common polymorphisms in the MDR1/ABCB1 transporter gene and susceptibility to colorectal cancer.Semantic proximity Read ↗

Intestinal PTGS2 mRNA levels, PTGS2 gene polymorphisms, and colorectal carcinogenesis.Semantic proximity Read ↗

NHERF1/EBP50 is a new marker in colorectal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.