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Article

Polymorphisms in NFkB, PXR, LXR and risk of colorectal cancer in a prospective study of Danes.

BMC cancer - 13 Sept 2010

Andersen Vibeke, Christensen Jane, Overvad Kim, Tjønneland Anne, Vogel Ulla

Abstract excerpt

BACKGROUND: Transcription factors and nuclear receptors constitute a link between exposure to heterocyclic amines and polycyclic aromatic hydrocarbons from meat and tobacco smoke and colorectal cancer (CRC) risk. The aim of this study was to investigate if polymorphisms in nuclear factor kappa-B, pregnane X receptor, and liver X receptor were associated with risk of CRC, and to investigate possible interactions...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20836841
DOI: 10.1186/1471-2407-10-484
PMCID: PMC2949803

Genes

NFKB1

Provenance

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