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Article

Detection of apolipoprotein E polymorphisms using PCR/ASO probes and Southern transfer: application for routine use.

Clinica chimica acta; international journal of clinical chemistry - 15 Aug 1990

Houlston R S, Wenham P R, Humphries S E

Abstract excerpt

The detection of apolipoprotein E genotypes is of importance both for diagnostic and research purposes. We have previously used the polymerase chain reaction to amplify a specific region of the apolipoprotein E gene which, when used in conjunction with allele specific oligonucleotide probes, permits the detection of the six common apolipoprotein genotypes. In our present report we have modified the above...

Topics

Alleles
Apolipoproteins E
Base Sequence
Blotting, Southern
DNA
DNA Probes
DNA-Directed DNA Polymerase
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Genetic

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Identifiers

PMID: 2397597
DOI: 10.1016/0009-8981(90)90086-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2397597-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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