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Article

The relationship between KRAS gene mutations and HLA class I antigen downregulation in the metastasis of non-small cell lung cancer.

The Journal of international medical research - 1 Oct 2013

He Xiao-Peng, Song Fu-Jie, Liu Xiang-Yan, Wang Zhou, Li Xiang-Xin, Liu Fan-Ying, Chen Gang, Jiang Wen-Peng

Abstract excerpt

OBJECTIVE: To investigate the association between v-Ki-ras2 Kirsten rat sarcoma viral oncogene homologue (KRAS) gene mutations and levels of human leucocyte antigen (HLA) class I antigen in primary lung tumours and metastatic lymph nodes of patients with non-small cell lung cancer (NSCLC). METHODS: Patients with NSCLC undergoing tumour resection were enrolled. KRAS codon 12 mutations were analysed in normal lung...

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PMID: 23975858
DOI: 10.1177/0300060513489801

Genes

KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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