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Article

A comparison of EGFR and KRAS status in primary lung carcinoma and matched metastases.

Human pathology - 1 Jan 2010

Monaco Sara E, Nikiforova Marina N, Cieply Kathleen, Teot Lisa A, Khalbuss Walid E, Dacic Sanja

Abstract excerpt

Epidermal growth factor receptor (EGFR) and v-Ki-ras 2 (KRAS; viral Kirsten rat sacoma 2 oncogene homolog) oncogenes are predictors of response to EGFR-targeted therapy in lung carcinomas. Morphologic heterogeneity of lung carcinomas is reflected at the molecular level and may confound interpretation of immunohistochemistry, fluorescence in situ hybridization, and mutational assays, which are all used for...

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Source

Identifiers

PMID: 19740513
DOI: 10.1016/j.humpath.2009.06.019

Genes

EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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