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Article

Effect of CYP3A422, POR28, and PPARA rs4253728 on sirolimus in vitro metabolism and trough concentrations in kidney transplant recipients.

Clinical chemistry - 1 Dec 2013

Woillard Jean-Baptiste, Kamar Nassim, Coste Sandra, Rostaing Lionel, Marquet Pierre, Picard Nicolas

Abstract excerpt

BACKGROUND: Recent studies have identified new candidate polymorphisms in the genes related to CYP3A activity or calcineurin inhibitor dose requirements in kidney transplant recipients. These genes and polymorphisms are CYP3A4 (cytochrome P450, family 3, subfamily A, polypeptide 4) (rs35599367-C>...

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Source

Identifiers

PMID: 23974086
DOI: 10.1373/clinchem.2013.204990

Genes

SRL
POR
PPARA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23974086-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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