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Article

Quantitative PCR measurement of tRNA 2-methylthio modification for assessing type 2 diabetes risk.

Clinical chemistry - 1 Nov 2013

Xie Peiyu, Wei Fan-Yan, Hirata Shoji, Kaitsuka Taku, Suzuki Tsutomu, Suzuki Takeo, Tomizawa Kazuhito

Abstract excerpt

BACKGROUND: Genetic variants in the human CDKAL1 (CDK5 regulatory subunit associated protein 1-like 1) gene have been associated with reduced insulin secretion and type 2 diabetes (T2D). CDKAL1 is a methylthiotransferase that catalyzes 2-methylthio (ms(2)) modification of the adenine at position...

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Share to Cyclin-Dependent Kinase 5
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23974085
DOI: 10.1373/clinchem.2013.210401

Genes

CDKAL1
CDK5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23974085-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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