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Article

tRNA Biology in the Pathogenesis of Diabetes: Role of Genetic and Environmental Factors.

International journal of molecular sciences - 6 Jan 2021

Arroyo Maria Nicol, Green Jonathan Alex, Cnop Miriam, Igoillo-Esteve Mariana

Abstract excerpt

The global rise in type 2 diabetes results from a combination of genetic predisposition with environmental assaults that negatively affect insulin action in peripheral tissues and impair pancreatic β-cell function and survival. Nongenetic heritability of metabolic traits may be an important contributor to the diabetes epidemic. Transfer RNAs (tRNAs) are noncoding RNA molecules that play a crucial role in protein...

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Share to Diabetes Mellitus, Type 2
Share to Gene-Environment Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Insulin-Secreting Cells

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Share to RNA Processing, Post-Transcriptional

Share to RNA, Transfer

Source

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Identifiers

PMID: 33419045
DOI: 10.3390/ijms22020496
PMCID: PMC7825315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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