Article
Genetic Markers for Later Remission in Response to Early Improvement of Antidepressants.
International journal of molecular sciences - 10 Jul 2020
Kang Hee-Ju, Kim Ki-Tae, Yoo Kyung-Hun, Park Yoomi, Kim Ju-Wan, Kim Sung-Wan, Shin Il-Seon, Kim Ju Han, Kim Jae-Min
Abstract excerpt
Planning subsequent treatment strategies based on early responses rather than waiting for delayed antidepressant action can be helpful. We identified genetic markers for later non-remission in patients exhibiting poor early improvement using whole-exome sequencing data of depressive patients treated in a naturalistic manner. Among 1000 patients, early improvement at 2 weeks (reduction in Hamilton Depression...
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