Article
Tyrosine kinase-2 gene polymorphisms are associated with ulcerative colitis and Crohn's disease in Turkish Population.
Clinics and research in hepatology and gastroenterology - 1 Sept 2015
Can Güray, Tezel Ahmet, Gürkan Hakan, Can Hatice, Yılmaz Bülent, Ünsal Gülbin, Soylu Ali Rıza, Ümit Hasan Celalettin
Abstract excerpt
BACKGROUND AND OBJECTIVE: Inflammatory bowel disease is a group of chronic inflammatory conditions affecting gastrointestinal tract. Lots of genes have been identified resulting in susceptibility to inflammatory bowel disease. Any polymorphism leading to functional modifications in tyrosine kinase-2 may precipitate excessive immune response in the intestinal mucosa. The aim of our study is to investigate the...
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