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Article

LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling.

Breast cancer research : BCR - 1 Jan 2013

Chang Joan, Nicolau Monica M, Cox Thomas R, Wetterskog Daniel, Martens John W M, Barker Holly E, Erler Janine T

Abstract excerpt

INTRODUCTION: Lysyl oxidase-like 2 (LOXL2) is a matrix-remodeling enzyme that has been shown to play a key role in invasion and metastasis of breast carcinoma cells. However, very little is known about its role in normal tissue homeostasis. Here, we investigated the effects of LOXL2 expression in normal mammary epithelial cells to gain insight into how LOXL2 mediates cancer progression. METHODS: LOXL2 was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 23971878
DOI: 10.1186/bcr3461
PMCID: PMC3978831

Genes

LOXL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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