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Article

Lipocalin 2 promotes breast cancer progression.

Proceedings of the National Academy of Sciences of the United States of America - 10 Mar 2009

Yang Jiang, Bielenberg Diane R, Rodig Scott J, Doiron Robert, Clifton Matthew C, Kung Andrew L, Strong Roland K, Zurakowski David, Moses Marsha A

Abstract excerpt

Here, we report that lipocalin 2 (Lcn2) promotes breast cancer progression, and we identify the mechanisms underlying this function. We first found that Lcn2 levels were consistently associated with invasive breast cancer in human tissue and urine samples. To investigate the function of Lcn2 in breast cancer progression, Lcn2 was overexpressed in human breast cancer cells and was found to up-regulate mesenchymal...

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Identifiers

PMID: 19237579
DOI: 10.1073/pnas.0810617106
PMCID: PMC2656179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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