Article
Combined genotype and haplotype tests for region-based association studies.
BMC genomics - 21 Aug 2013
Zakharov Sergii, Wong Tien Yin, Aung Tin, Vithana Eranga Nishanthie, Khor Chiea Chuen, Salim Agus, Thalamuthu Anbupalam
Abstract excerpt
BACKGROUND: Although single-SNP analysis has proven to be useful in identifying many disease-associated loci, region-based analysis has several advantages. Empirically, it has been shown that region-based genotype and haplotype approaches may possess much higher power than single-SNP statistical...
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