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Article

BAP1 protein is a progression factor in malignant pleural mesothelioma.

Pathology oncology research : POR - 1 Jan 2014

Arzt Lisa, Quehenberger Franz, Halbwedl Iris, Mairinger Thomas, Popper Helmut H

Abstract excerpt

Human malignant pleural mesothelioma (MPM) is an aggressive cancer due to former asbestos exposure with little knowledge about prognostic factors of outcome and resistance to conventional therapy. BRCA1-associated protein 1 (BAP1) is a tumor suppressor gene that is frequently lost in MPM. Germline mutations of BAP1 predispose to several different tumors including malignant mesothelioma. Our study aimed to clarify...

Read the complete abstract on PubMed

Topics

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Share to Asbestos
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mesothelioma, Malignant

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Source

Identifiers

PMID: 23963927
DOI: 10.1007/s12253-013-9677-2

Genes

BAP1
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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