Article
A single nucleotide polymorphism on the GALNT14 gene as an effective predictor of response to chemotherapy in advanced hepatocellular carcinoma.
International journal of cancer - 1 Mar 2014
Yeh Chau-Ting, Liang Kung-Hao, Lin Chen-Chun, Chang Ming-Ling, Hsu Cheng-Lung, Hung Chien-Fu
Abstract excerpt
Previously, a pilot genome-wide association study has identified candidate single nucleotide polymorphism predictors for the therapeutic response of 5-fluorouracil, mitoxantrone and cisplatin (FMP) combination chemotherapy in advanced hepatocellular carcinoma (HCC). Here, we conducted a prospective confirmatory study to examine the predictive value of rs9679162 (located on GALNT14 gene) for the therapeutic...
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