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Article

GALNT14 genotype-guided chemoembolization plus sorafenib therapy in hepatocellular carcinoma: a randomized trial.

Hepatology international - 1 Feb 2022

Chen Wei-Ting, Lin Shi-Ming, Lee Wei-Chen, Wu Ting-Jung, Lin Chen-Chun, Shen Chien-Heng, Chang Ming-Ling, Lin Chih-Lang, Yeh Chau-Ting

Abstract excerpt

BACKGROUND: GALNT14-rs9679162 "TT" genotype is associated with favorable clinical outcomes in hepatocellular carcinoma (HCC) treated by transarterial chemoembolization (TACE). We investigated whether patients with GALNT14-rs9679162 "non-TT" unfavorable genotype benefited from chemoembolization plus sorafenib combination therapy. METHODS: Intermediate stage HCC patients were recruited for GALNT14-rs9679162...

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Share to Antineoplastic Agents
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PMID: 34982369
DOI: 10.1007/s12072-021-10283-7

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