Article
GALNT14 SNP as a potential predictor of response to combination chemotherapy using 5-FU, mitoxantrone and cisplatin in advanced HCC.
Pharmacogenomics - 1 Jul 2011
Liang Kung-Hao, Lin Chen-Chun, Yeh Chau-Ting
Abstract excerpt
AIM: Despite the availability of targeted anticancer agents, combination chemotherapy remains an option for patients with far advanced hepatocellular carcinoma. We aimed to identify germline SNP markers in order to predict the objective response of combination chemotherapy using 5-fluorouracil, mitoxantrone and cisplatin (FMP). MATERIALS & METHODS: This study was conducted in two steps. First, a genome-wide...
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