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Article

Anti-obesity phenotypic screening looking to increase OBR cell surface expression.

Journal of biomolecular screening - 1 Jan 2014

Kim Tae-Hee, Choi Dong-Hwa, Vauthier Virginie, Dam Julie, Li Xiaolan, Nam Yeon-Ju, Ko YoonAe, Kwon Ho Jeong, Shin Sang Hoon, Cechetto Jonathan, Soloveva Veronica, Jockers Ralf

Abstract excerpt

The leptin receptor, OBR, is involved in the regulation of whole-body energy homeostasis. Most obese people are resistant to leptin and do not respond to the hormone. The prevention and reversal of leptin resistance is one of the major current goals of obesity research. We showed previously that...

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Source

Identifiers

PMID: 23958651
DOI: 10.1177/1087057113499185

Genes

JAK2
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23958651-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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