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Article

Selection of Leptin Surrogates by a General Phenotypic Screening Method for Receptor Agonists.

Biomolecules - 9 Apr 2024

Wang Tao, Chen Xixi, Yang Guang, Shi Xiaojie

Abstract excerpt

There is a high demand for agonist biomolecules such as cytokine surrogates in both biological and medicinal research fields. These are typically sourced through natural ligand engineering or affinity-based screening, followed by individual functional validation. However, efficient screening methods for identifying rare hits within immense libraries are very limited. In this research article, we introduce a...

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Identifiers

PMID: 38672473
DOI: 10.3390/biom14040457
PMCID: PMC11047824

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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