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Article

Cannabinoid Receptor 2 as Antiobesity Target: Inflammation, Fat Storage, and Browning Modulation.

The Journal of clinical endocrinology and metabolism - 1 Sept 2016

Rossi Francesca, Bellini Giulia, Luongo Livio, Manzo Iolanda, Tolone Salvatore, Tortora Chiara, Bernardo Maria Ester, Grandone Anna, Conforti Antonella, Docimo Ludovico, Nobili Bruno, Perrone Laura, Locatelli Franco, Maione Sabatino, Del Giudice Emanuele Miraglia

Abstract excerpt

CONTEXT: Obesity is associated with a low-grade inflammatory state and adipocyte (ADP) hyperplasia/hypertrophy. Obesity inhibits the "browning" of white adipose tissue. Cannabinoid receptor 2 (CB2) agonists reduce food intake and induce antiobesity effect in mice. A common missense CB2 variant, Q63R, causes CB2-reduced function. OBJECTIVE: To evaluate the influence of CB2 receptor on the modulation of childhood...

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Identifiers

PMID: 27294325
DOI: 10.1210/jc.2015-4381

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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