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Article

Criteria and prediction models for mismatch repair gene mutations: a review.

Journal of medical genetics - 1 Dec 2013

Win Aung Ko, Macinnis Robert J, Dowty James G, Jenkins Mark A

Abstract excerpt

One of the strongest predictors of colorectal cancer risk is carrying a germline mutation in a DNA mismatch repair (MMR) gene. Once identified, mutation carriers can be recommended for intensive screening that will substantially reduce their high colorectal cancer risk. Conversely, the relatives of carriers identified as non-carriers can be relieved of the burden of intensive screening. Criteria and prediction...

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Share to Adaptor Proteins, Signal Transducing
Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mismatch Repair

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Share to MutL Protein Homolog 1

Share to MutS Homolog 2 Protein

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Source

Identifiers

PMID: 23956446
DOI: 10.1136/jmedgenet-2013-101803

Genes

PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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