Article
Validation of Prediction Models for Mismatch Repair Gene Mutations in Koreans.
Cancer research and treatment - 1 Apr 2016
Lee Soo Young, Kim Duck-Woo, Shin Young-Kyoung, Ihn Myong Hoon, Lee Sung Min, Oh Heung-Kwon, Ku Ja-Lok, Jeong Seung-Yong, Lee Jae Bong, Ahn Soyeon, Won Sungho, Kang Sung-Bum
Abstract excerpt
PURPOSE: Lynch syndrome, the commonest hereditary colorectal cancer syndrome, is caused by germline mutations in mismatch repair (MMR) genes. Three recently developed prediction models for MMR gene mutations based on family history and clinical features (MMRPredict, PREMM(1,2,6), and MMRPro) have been validated only in Western countries. In this study, we propose validating these prediction models in the Korean...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
