Article
Evolving approach and clinical significance of detecting DNA mismatch repair deficiency in colorectal carcinoma.
Seminars in diagnostic pathology - 1 Sept 2015
Shia Jinru
Abstract excerpt
The last two decades have seen significant advancement in our understanding of colorectal tumors with DNA mismatch repair (MMR) deficiency. The ever-emerging revelations of new molecular and genetic alterations in various clinical conditions have necessitated constant refinement of disease terminology and classification. Thus, a case with the clinical condition of hereditary non-polyposis colorectal cancer as...
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