Article
The role of lipoxygenases in epidermis.
Biochimica et biophysica acta - 1 Mar 2014
Krieg Peter, Fürstenberger Gerhard
Abstract excerpt
Lipoxygenases (LOX) are key enzymes in the biosynthesis of a variety of highly active oxylipins which act as signaling molecules involved in the regulation of many biological processes. LOX are also able to oxidize complex lipids and modify membrane structures leading to structural changes that play a role in the maturation and terminal differentiation of various cell types. The mammalian skin represents a tissue...
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