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Article

Prevention of airway allograft tolerance by polyinosinic:polycytidylic acid requires type I interferon responsiveness for mouse airway obliteration.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Sept 2013

Miller Hannah L, Shah Pali D, Orens Jonathan B, McDyer John F

Abstract excerpt

BACKGROUND: Respiratory RNA viruses are associated with bronchiolitis obliterans syndrome (BOS) in lung transplant recipients (LTRS); however, the immune mechanisms that regulate airway obliteration remain incompletely understood. METHODS: Using the mouse heterotopic tracheal transplant model of obliterative airway disease (OAD), we studied the role of double-stranded (ds)RNA using polyinosinic:polycytidylic acid...

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Identifiers

PMID: 23953819
DOI: 10.1016/j.healun.2013.06.017
PMCID: PMC4203313

Genes

DST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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