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Article

Adoptive transfer of murine syngeneic graft-vs.-host disease by CD4+ T cells.

Journal of leukocyte biology - 1 Dec 2007

Bryson J Scott, Jennings C Darrell, Brandon Jason A, Perez Jacqueline, Caywood Betty E, Kaplan Alan M

Abstract excerpt

Syngeneic graft-vs.-host disease (SGVHD) develops in rodents following the treatment of lethally irradiated, bone marrow (BM) reconstituted animals with a short course of the immunosuppressive agent cyclosporine A (CsA). Using an in vivo depletion approach, we recently demonstrated that CD4(+), but not CD8(+), T cells participated in inducing SGVHD. Studies were therefore undertaken to adoptively transfer SGVHD...

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Identifiers

PMID: 17726153
DOI: 10.1189/jlb.0307183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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