Article
Failure of chimerism formation and tolerance induction from Fas ligand mutant bone marrow donors after nonmyeloablative conditioning.
Transplant immunology - 1 Dec 2012
Nusair Samir, Gincberg Galit, Almogi-Hazan Osnat, Breuer Raphael, Or Reuven, Wallach-Dayan Shulamit B
Abstract excerpt
Formation of donor-recipient mixed chimerism after nonmyeloablative conditioning allows co-existence of donor and recipient hematopoietic stem cells, with solid organ allograft tolerance and less likeliness of graft versus host development. Using a post-transplant bronchiolitis obliterans murine model, we aimed to test the hypothesis that allograft preservation after mixed chimerism formation is dependent on the...
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