Article
Identification of the effects of aging-related gene-matrix metalloproteinase on allograft outcomes in kidney transplantation.
Transplantation proceedings - 1 Jan 2000
Han S S, Lee H, Oh Y J, Lee J P, Kim S, Ha J, Kim S J, Park M H, Kim Y S, Kim D K
Abstract excerpt
BACKGROUND: Aging plays a profound role in the ability of the kidney to function. Aging which varies among individuals, has been associated with the matrix metalloproteinase (MMP) 7 and 20 genes. This study was conducted to analyze correlations between polymorphisms of MMP genes [rs880197 in MMP7 (A>T) and rs1711437 in MMP20 (G>A)] and transplant outcomes in 235 recipients. METHODS: Transplant outcomes were...
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