Article
[Impact of interleukin-10 and interleukin-28 gene polymorphisms on the development and course of lupus nephritis].
Terapevticheskii arkhiv - 1 Jan 2015
Krasnova T N, Samokhodskaya L M, Ivanitsky L V, Korogodina A D, Borisov E N, Nikiforova N V, Novikov P I, Kamalov A A, Mukhin N A
Abstract excerpt
AIM: To assess the relationship of the carriage of IL-10-1080 G/A and IL-28 rs8099917 C/T polymorphisms to the course of lupus nephritis (LN). SUBJECTS AND METHODS: Ninety-nine patients with systemic lupus erythematosus (SLE), including 68 with LN, were examined. Gene polymorphisms were analyzed using standard molecular genetic techniques. The frequency of the clinical manifestations of LN was analyzed; renal...
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