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Article

Genetic polymorphisms in MMP7 and reduced serum levels associate with the development of bronchiolitis obliterans syndrome after lung transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Jun 2010

Kastelijn Elisabeth A, van Moorsel Coline H, Ruven Henk J, Karthaus Vincent, Kwakkel-van Erp Johanna M, van de Graaf Ed A, Zanen Pieter, van Kessel Diana A, Grutters Jan C, van den Bosch Jules M

Abstract excerpt

BACKGROUND: Pulmonary epithelium is the primary target of injury in the development of bronchiolitis obliterans syndrome (BOS) after lung transplantation. Matrix metalloproteinases (MMP)-8 and -9 already have been implicated in the pathogenesis of BOS. MMP-7, which is involved in the repair of th...

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Identifiers

PMID: 20347338
DOI: 10.1016/j.healun.2010.01.008

Genes

MMP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20347338-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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