Article
Association of methylenetetrahydrofolate reductase T677 allele with early development of chronic allograft nephropathy.
Clinical biochemistry - 1 Oct 2004
Viklický Ondrej, Hubácek Jaroslav A, Kvasnicka Jan, Matl Ivo, Voska Ludek, Skibová Jelena, Teplan Vladimír, Vítko Stefan
Abstract excerpt
OBJECTIVES: The aim of this study was to evaluate the role of genetic polymorphisms on the development of chronic allograft nephropathy (CAN). DESIGN AND METHODS: Using the polymerase chain reaction (PCR), polymorphisms of methylenetetrahydrofolate reductase (MTHFR C677T), interleukin-6 (IL-6 G-174C) and CD14 (C-260T) were evaluated in 92 kidney transplant recipients with stable renal graft function and no signs...
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