Article

A highly sensitive and versatile fluorescent biosensor for pathogen nucleic acid detection based on toehold-mediated strand displacement initiated primer exchange reaction

2022-03-08

Abstract excerpt

Existing methods for pathogen nucleic acid detection, such as PCR, require complicated operation and expensive facility. Here, we report a simple and versatile strategy for highly sensitive detection of pathogen nucleic acid based on toehold-mediated strand displacement initiated primer exchange amplification (t-PER). In the presence of target, the blocked hairpin substrate would be released by toehold-mediated st...

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Literature Corpus work: bdd4c0e0-49b2-51a1-b5f1-7dcc562a48fe
DOI: 10.21203/rs.3.rs-1388780/v1

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