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Article

Effect of HIV-1 subtypes on disease progression in rural Uganda: a prospective clinical cohort study.

PloS one - 1 Jan 2013

Ssemwanga Deogratius, Nsubuga Rebecca N, Mayanja Billy N, Lyagoba Frederick, Magambo Brian, Yirrell Dave, Van der Paal Lieve, Grosskurth Heiner, Kaleebu Pontiano

Abstract excerpt

OBJECTIVE: We examined the association of HIV-1 subtypes with disease progression based on three viral gene regions. DESIGN: A prospective HIV-1 clinical cohort study in rural Uganda. METHODS: Partial gag, env and pol genes were sequenced. Cox proportional hazard regression modelling was used to estimate adjusted hazard ratios (aHRs) of progression to: CD4≤250, AIDS onset and death, adjusted for sex, age and CD4...

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Identifiers

PMID: 23951241
DOI: 10.1371/journal.pone.0071768
PMCID: PMC3741119

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Source receipt: pubmed, retrieved 7 Sept 2026.

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