Article
Impact of HIV-1 viral subtype on disease progression and response to antiretroviral therapy.
Journal of the International AIDS Society - 3 Feb 2010
Easterbrook Philippa J, Smith Mel, Mullen Jane, O'Shea Siobhan, Chrystie Ian, de Ruiter Annemiek, Tatt Iain D, Geretti Anna Maria, Zuckerman Mark
Abstract excerpt
BACKGROUND: Our intention was to compare the rate of immunological progression prior to antiretroviral therapy (ART) and the virological response to ART in patients infected with subtype B and four non-B HIV-1 subtypes (A, C, D and the circulating recombinant form, CRF02-AG) in an ethnically diverse population of HIV-1-infected patients in south London. METHODS: A random sample of 861 HIV-1-infected patients...
Topics
- Adult
- Anti-HIV Agents
- Antiretroviral Therapy, Highly Active
- CD4 Lymphocyte Count
- CD4-Positive T-Lymphocytes
- Disease Progression
- Female
- Genotype
- HIV Infections
- HIV-1
