Article
HIV Type 1 Disease Progression to AIDS and Death in a Rural Ugandan Cohort Is Primarily Dependent on Viral Load Despite Variable Subtype and T-Cell Immune Activation Levels.
The Journal of infectious diseases - 15 May 2015
Eller Michael A, Opollo Marc S, Liu Michelle, Redd Andrew D, Eller Leigh Anne, Kityo Cissy, Kayiwa Joshua, Laeyendecker Oliver, Wawer Maria J, Milazzo Mark, Kiwanuka Noah, Gray Ronald H, Serwadda David, Sewankambo Nelson K, Quinn Thomas C, Michael Nelson L, Wabwire-Mangen Fred, Sandberg Johan K, Robb Merlin L
Abstract excerpt
BACKGROUND: Untreated human immunodeficiency virus type 1 (HIV) infection is associated with persistent immune activation, which is an independent driver of disease progression in European and United States cohorts. In Uganda, HIV-1 subtypes A and D and recombinant AD viruses predominate and exhi...
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