Article
HIV-1 subtype distribution trends and evidence of transmission clusters among incident cases in a rural clinical cohort in southwest Uganda, 2004-2010.
AIDS research and human retroviruses - 1 Mar 2013
Kapaata Anne, Lyagoba Frederick, Ssemwanga Deogratius, Magambo Brian, Nanyonjo Maria, Levin Jonathan, Mayanja Billy N, Mugasa Claire, Parry Chris M, Kaleebu Pontiano
Abstract excerpt
The high diversity of HIV-1 has been shown to affect disease progression, transmission, and response to antiretroviral therapy and may influence HIV vaccine design. We describe the distribution trends of HIV-1 subtypes over a 7-year period among incident cases in a rural clinical cohort in Southwest Uganda and identify transmission clusters. Viral RNA was extracted from cryopreserved plasma samples from 94...
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