Article
quantitative assessment of the influence of cytochrome P450 1A2 gene polymorphism and colorectal cancer risk.
PloS one - 1 Jan 2013
Zhao Yuan, Chen Zi-Xian, Rewuti Abudouaini, Ma Yu-Shui, Wang Xiao-Feng, Xia Qing, Fu Da, Han Yu-Song
Abstract excerpt
Cytochrome P450 1A2 (CYP1A2) encodes a member of the cytochrome P450 superfamily of enzymes, which play a central role in activating and detoxifying many carcinogens and endogenous compounds thought to be involved in the development of colorectal cancer (CRC). The CYP1A2*C (rs2069514) and CYP1A2*F (rs762551) polymorphism are two of the most commonly studied polymorphisms of the gene for their association with...
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